Sugary foods sure do taste good, but the only good they are doing is electrifying your taste buds. The ugly truth about sugar is it causes weight gain, high cholesterol levels, cardiovascular disease and even affects your mental awareness. Even worse, sugar is a big factor when it comes to tooth decay and periodontal disease. We’re marking up sugar to be the bad guy, because it is!

Of course, you cannot cut sugar completely out of your life. It exists in plenty of processed foods, not just in candy and sodas. You’d have to go cold-turkey on a lot of your favorites, including cereals, saucy foods, potato chips and especially ice cream. Even healthier options like apples and citrus fruits have a high sugar concentration. Sugar is bountiful in our diets, but if you cut down the sugar intake, your oral and overall health will both see a huge difference!

How to Cut Back on Sugar

Cutting down on sugar is pretty easy if you think about it. You control what type of foods and drinks go into your mouth after all. So, let’s take a look at some of the most common sugar fiends that exist.

Let’s start with sodas! Sodas make the most sense. Let’s look at their sugar concentration. In a regular 12oz. can, most sodas have anywhere between 30-50g of sugar. That’s a lot! Cutting out sodas completely may cause you to go through withdrawal symptoms including anxiety, so medical experts believe a greater alternative is to start cutting your soda intake by half in moderation until soda is no longer something you’re drinking on a needless basis.

What’s wrong with sport drinks? Unless you’re an active athlete, you don’t need to be drinking sport drinks day in and day out. While they may have a high number of electrolytes, it also has plenty of sugar. Sport drinks are meant to get athletes through their sport, and you’ll often see them drink plenty of water too. If you have a sport drink regularly without combining it with physical activity, it could lead to weight gain and sensitive teeth.

Say goodbye to processed foods! Amongst the many things in your diet, cookies, cakes, pastries and breakfast cereals are notorious for their high sugar concentration. For better or worse, the only benefits these foods provide is a sugar rush that’ll have you craving sugar throughout the rest of the day. There’s plenty of other options you can try instead that’re just as fulfilling, including oat foods, unsalted raw nuts and fruit-based snacks.

Throw away the candies and sweets! One thing that we’ve grown accustomed to is a limitless supply of candy. Candy tastes good, and we keep plenty of it near us for satisfying our taste buds. That’s terrible! If you’re a candy lover, not only are you exposing your teeth to dangerous sugar amounts, but you’re ruining your sense of taste! Start cutting back on the amount of candies you eat and focus more on fresh fruits, sugar-free gum and even dark chocolate.

Ways Your Teeth Benefit from Less Sugar Consumption

Our teeth are very important to us and cutting down on sugar is perhaps one of the greatest things we can do for them. When you consume sugar, the millions of bacteria in your mouth feed on it, breaking it down into an acid that eats at our teeth. As a result, it can cause tooth decay. The funny part is, sipping from a 12oz. can is worse than chugging down a 2-liter bottle as you’re exposing your teeth to sugar longer, letting bacteria do its finest work inside your mouth.

So, by cutting down on sugar you can stop tooth decay! Other things that can help prevent tooth decay alongside cutting down your sugar consumption is chewing sugar-free gum to promote salivation, brushing your teeth before breakfast and after dinner, and flossing to clean the other half of your teeth a toothbrush can’t reach.

Sugary foods also cause teeth discoloration. It’s embarrassing to have yellow or brown teeth, especially since your smile is the biggest first impression you can make with anyone, beating out other factors such as body language, appearance and quality of speech. Teeth staining is largely due to sugary drinks, coffee and tea. Moreover, soft drinks also cause cavities, which can turn your teeth black. By cutting down sugar in your diet, you can stop your teeth from turning into weird colors.

Your significant other will love this too! If you cut down on sugar, you’ll have better breath! All those acids that are a result of sugar consumption actually smell, and it’s easy to tell. To see just how bad your breath smells after drinking a soda, wait 30 minutes and lick the palm of your hand, then smell it. You’ll definitely notice a difference!

Lastly, you’ll feel a difference in your oral health. Your teeth will feel healthier, stronger and not as sensitive, it’ll feel like weight has been lifted off of your teeth.

As a final note, you don’t have to cut our sugar completely, just consume less sugar than you have been. Sugar itself is everywhere and is near impossible to avoid. However, so long as you take the initiative to eat and drink less sugary foods you should be just fine. This also includes that you brush your teeth, floss, use mouthwash and visit the dentist on a bi-annual basis to get your cleanings done.

Peptide therapeutics, due to their various advantages such as high stability, selectivity, safety, efficacy, bioavailability, and tolerability offers wide applications over the other therapeutics classes. Over 7,000 naturally occurring peptides have been identified, which have crucial roles in human physiology, which include hormones, neurotransmitters, growth factors, ion channel, and ligands. The structure of these peptides is usually complex and these conformations depending upon their environment.

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Manufacturers are focusing on developments in biologics and biopharmaceutical peptides and proteins for application in diagnostics and therapies. According to the data published in Drug Discovery Today, in January 2015, around 140 peptide therapeutics are currently evaluated in clinical trials. Peptide therapeutics are increasingly been used for therapeutics in metabolic diseases and oncology. Rising incidence of metabolic diseases such as Diabetes mellitus type 2 (T2DM) and Obesity are expected to be factors driving growth of the market. According to World Health Organization (WHO) 2017 data findings, the number people suffering from diabetes have increased from 108 million to 422 million in 2014.

Similarly, the world obesity rate has increased three times since 1975 and in 2016, over 1.9 billion adults (18 year and above) were estimated to be overweight. According to the Centers for Disease Control and Prevention (CDC) October 2017 data findings, in 2011–2012, 78 million U.S. adults had low-density lipoprotein cholesterol levels, which put them at high risk of heart disease and stroke. However, high prices of products is expected to negatively impact the overall market growth.

Among the metabolic disorders, the risk of developing type 1 and type 2 diabetes is related to the combination of variants in multiple genes. In rare cases, patients which are monogenic having single gene mutation which can lead to diabetes. The first peptide to be administrated therapeutically was insulin and has been used in the treatment of diabetes. Development of novel analogues such as lispro insulin that is an injection to be taken prior to meal, has also aided in growth of the market. Another important peptide is glucagon like peptide-1 (GLP-1), which has insulin-releasing properties and also helps to suppress the glucagon level. The glucose dependent action of GLP-1 is more potent to regulate glucose level after a meal. These properties of peptides has aided in development of novel therapeutics and is expected to drive growth of the market in the near future. According to the data published in the January 2015, in Drug Discovery Today Journal, total 60 peptides-based drugs such as viscozyme, pulmozyme, glucagen are available in the market and number of other therapeutic peptides such as cpd86 (preclinical), MOD-6030 (preclinical), MAR709 (II) and semaglutide (III) are currently evaluated in different phase of clinical trial thus, strong pipeline is expected to propel growth of the peptide therapeutics in metabolic disorders market in the near future.

Key players in the market are focusing on collaborations and new product launches, in order to enhance their market share. For instance, Rhythm Pharmaceuticals Inc. is engaged in developing obesity drug called setmelanotide a Melanocortin 4 receptor (MC4R) agonist peptide that is meant to be injected daily to regulate the body energy balance and appetite. Moreover, in June 2017, Rhythm Pharmaceuticals and Camurus AB released the positive initial results from ongoing Phase 1A clinical trial, which evaluated the pharmacokinetics and tolerability of an extended-release formulation of setmelanotide.

The company is also conducting trials for the treatment of extremely rare metabolic disorders such as Pro-opiomelanocortin (POMC) and Leptin receptor (LepR) deficiency obesity. Furthermore, in September, 2017, Zealand Pharma and Torrey Pines Institute for Molecular Studies entered into a research collaboration for multi-target research to identify novel peptide-based products by using Torrey Pines Institute for Molecular Studies (TPIMS’s) peptide libraries. This collaboration will help to develop specialty medicines to treat metabolic and gastrointestinal diseases.

Colon and rectal cancer are often grouped together, as they have many common features. Rate of colorectal cancer is increasing among the millennials in the U.S. The American Cancer Society (ACS) estimates that there will be around 97,220 new cases of colon cancer and around 43,030 new cases of rectal cancer registered in the U.S. in 2018. Moreover, owing to increasing risk of colorectal cancer, in May 2018, ACS updated their guidelines for colorectal cancer screenings and recommended to start colorectal cancer screening at the age of 45 rather than at the age of 50.

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For instance, according to February 2018 data findings of the American Cancer Society (ACS), colorectal cancer is the third most common cancer diagnosed in both men and women in the U.S.

Moreover, according to the Center for Disease Control and Prevention (CDC), in 2014, around 139,992 people in the U.S. were diagnosed with colorectal cancer, including 73,396 men and 66,596 women. Among which, around 51,651 people in the U.S. died due to colorectal cancer, including 27,134 men and 24,517 women. Furthermore, according to 2012 data findings of the World Health Organization (WHO), colorectal cancer is the third most common cancer in men (746,000 cases, 10.0% of the total) and the second most common in women (614,000 cases, 9.2% of the total) worldwide, in 2012. Furthermore, around 55% of these cases occurred in developed regions.

Increasing number of research and development (R&D) studies by government and private healthcare organizations is also fueling growth of colon and rectal cancer drugs market. For instance, the American Cancer Society (ACS) spend US$ 54 million on colon and rectal cancer research involving 92 research grants, till March 2018.

Lack of development in the neoadjuvant/adjuvant pipeline agents for the treatment of high risk colorectal cancer resulted in slower growth of colon and rectal cancer drugs market. For instance, according to the data published in the National Center for Biotechnology Information (NCBI) in April 2016, there is lack of clinical trials of systemic adjuvant, neoadjuvant, and perioperative chemotherapy for the treatment of colorectal liver metastases (CRLM). These offers lucrative opportunity for the key players to develop new treatment therapy using neoadjuvant agents for resected patients.

On the basis of region, the global colon and rectal cancer drugs market is segmented into North America, Latin America, Europe, Middle East, Asia Pacific, and Africa. North America holds dominant position in the colon and rectal cancer drugs market, followed by Europe. This is owing to increasing incidence rate of colorectal cancer in these regions. According to the World Cancer Research Fund International, in 2012, Republic of Korea had the highest rate of colorectal cancer, followed by Slovakia and Hungary. Furthermore, since few years, large number of colorectal cancer incidences were registered in Oceania and Europe region, while it shows lowest incidence rates in Africa and Asia region.

The rising popularity of alternative medicine has been remarkable worldwide over the last few decades. The uniqueness of alternative medicine in Houston is its holistic approach to treat a whole body instead of just addressing the problems with use of harmful drugs and surgical session. Among the array, acupuncture, a branch of TCM meanwhile, has gained enormous trust among people with its recognition by healthcare industry and insurance companies. Here, the writing highlights on how acupuncture can be proved beneficial for women’s health.Five Ways Alternative Medicine in Houston Can Benefit WomenChallenges InfertilityIt’s been proved that stress and fatigue often cause cramps in the fallopian tube as well as uterus and get in the way of normal implantation of fertilized eggs. As an alternative medicine in Houston, TX acupuncture plays a major role to neutralize the effects of trauma by discharging endorphins (the feel-good hormone) in the brain. Thus, through normalizing menstrual cycle, lessening stress, and enhancing flow of blood to the ovaries, uterus, acupuncture reinforces the reproductive system enabling it to nourish and carry the egg to its term.Lessens Pregnancy IssuesFor many, pregnancy issues like morning sickness, back pains, swelling legs, heartburn, cramping legs are painful experiences, which can be wonderfully handled with alternative medicine in Houston, TX. Your acupuncturist will apply acupuncture needles to certain acupoints to reduce nausea as well, for activating nerves to release endorphins and stop back pain, swelling or cramping legs.Menstrual PainMenstrual pain is quite widespread among women, whilst the mass used to intake medications directly from chemists shops which emerge with many side effects. Consider, having alternative medicine in Houston, TX; the good news for you it that the natural treatment of acupuncture is fantastic to deal with short-term excessive ache that overwhelm you all through the day during menstrual period.Cosmetic and Skin RejuvenationThe benefit of cosmetic acupuncture has been cherished from the ancient era as a beauty secret which can naturally revitalize skin tone with increased moisture and balancing skin nutrients. While you spend money like anything to use costly anti-ageing skin creams which do nothing more than spoiling the normal glow of skin, acupuncture basically nourishes the inner elements that contribute to aging process. It can help soften under-eye fine lines, deeper wrinkles, and redness with enhanced hydration, blood circulation, and tightening skin muscles to get back youthful shiny skin.Weight LossStress, insomnia, and weariness are some of the major causes that trigger weight gain. If you’re one among the victims struggling to fight back obese with unscientific dieting, hours of gym and workouts, try a few sessions of acupuncture and see how amazingly it can alleviate the root causes by lessening stress. With activation of feel-good neurotransmitters, acupuncture can reduce your craving, control hunger, and help melting excess fat by balancing calorie intake and make you feel healthy and lively.